Capabilities and Resources
The Emory Chemical Biology Discovery Center (ECBDC) is a nationally recognized academic high throughput screening center involved in local, national and international drug discovery programs. The ECBDC offers state-of-the-art HTS and HCS capabilities with multiple integrated robotic systems and a large collection of small molecule compound libraries. With these platforms, the ECBDC aims to accelerate translation of basic research discoveries and high throughput biology into novel targets and therapeutics.
- December 2020: Congratulations Cong Tang, Xiulei Mo, and the team with new publication "Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling. Cell. Chem. Biol. 2020 Dec 4:S2451-9456(20)30473-6. doi: 10.1016/j.chembiol.2020.11.010."
- September 2020: Andrey Ivanov team discovered a new biomarker, MKK3, for racial disparity in breast cancer patients of African Americans. This work, published in J. Transl. Med., 2020, 18, #334, has been recognized by the American Association for Cancer Research “Scholar-in-Training Award” to present at the AACR Virtual Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, being held from October 2-4, 2020.
- September 2020: The FREE registration for the 9th International Chemical Biology Society 2020 Conference: ICBS2020 Virtual is now OPEN!
- August 2020: Congratulations to Dr. Andrey Ivanov, awardee of the Winship Lung cancer SPORE Career Enhancement Program Grant “Discovery of new therapeutic options for lung cancer patients with lost tumor suppressor genes”!
- July 2020: Congratulations Dr. Yuhong Du and the team with new publication: "Development of a miniaturized 3D organoid culture platform for ultra-high throughput screening", J. Mol. Cell. Biol., 2020, doi: 10.1093/jmcb/mjaa036
- June 2020: A review paper “Online informatics resources to facilitate cancer target and chemical probe discovery” by Xuan Yang, Haian Fu, and Andrey Ivanov is featured on the cover of the RSC Medicinal Chemistry. RSC Medicinal Chemistry, 2020, 11, 611 – 624
- May 2020: Join us for the Biological Discovery through Chemical Innovation (BDCI) Virtual Seminars!
- February 2020: Congratulations to Dr. Andrey Ivanov, awardee of the Winship American Cancer Society Institutional Research Grant (ACS/IRG) “Structural Basis for MKK3-mediated MYC Activation”!
- January 2020: Congratulations to Dr. Xiulei Mo! Dr. Mo was selected for the Woodruff Health Sciences Center (WHSC)’s 10X Single Cell Sequencing Seed Grant.
- October 2019: A book chapter "Explore Protein-Protein Interactions for Cancer Target Discovery Using the OncoPPi Portal" by Dr. Andrey Ivanov presents a guide to explore the OncoPPi network using the Emory OncoPPi Portal to facilitate cancer biology. Protein-Protein Interaction Networks pp 145-164.
- October 2019: “Emory Chemical Biology Discovery Center becomes an operational hub for ASSAY and HTS in the Open Drug Discovery Center for Alzheimer’s Disease (Open-AD Center). The Open-AD Center led by Emory is supported by a new $37 million grant from the NIH/NIA.”
- August 2019: Congratulations to Dr. Xiulei Mo! Dr. Mo was selected for the Career Enhancement Program award by the NCI's Emory Lung Cancer SPORE.
- April 2019: ICBS Emory Young Scholar Chapter hosted the spring event on April 12th, 2019. This is the second major event of the student/postdoc organization since its launch in the summer of 2018. Centered around the theme “Chemical Biology in the Drug Discovery and Development”, Dr. Zaneta Nicolovska-Coleska (University of Michigan) talked about the chemical biology and drug discovery research in academia, Dr. Douglas Auld (Novartis) presented the opportunities of industry-academic collaborations with Novartis, and Dr. Kallol Basu (Merck Process) presented the development of a green and sustainable manufacturing process for a clinical candidate drug MK-7264
- March 2019: Congratulations Dr. Xiulei Mo with the Cell Chemical Biology paper "HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers"! Cell Chem. Biol., 2019, 26, 331-339.
- January 2019: Effective January 1, 2019, the Pharmacology Department became "The Department of Pharmacology and Chemical Biology.”
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