Capabilities and Resources

Overview

The Emory Chemical Biology Discovery Center (ECBDC) is a nationally recognized academic high throughput screening center involved in local, national and international drug discovery programs. The ECBDC offers state-of-the-art HTS and HCS capabilities with multiple integrated robotic systems and a  large collection of small molecule compound libraries.  With these platforms, the ECBDC aims to accelerate translation of basic research discoveries and high throughput biology into novel targets and therapeutics. 

Research Highlights

Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease

Dr. Keqiang Ye’s team worked with Dr. Yuhong Du for high throughput screening at ECBDC and identified an orally bioactive and brain permeable δ-secretase inhibitor that is effective in mouse models of Alzheimer’s disease.

Inhibition of delta-secretase

Click here for Nature Communications article.

Click here to read article at Pubmed.gov.

News

View All News>>